Technologies
Methods and platforms which never settle.
AVITI Element Biosciences
The AVITI System by Element Biosciences is a benchtop sequencer designed for high performance, cost efficiency, and flexibility. It features dual independent flow cells for parallel or independent operation, enabling flexibility in throughput from low to full. The system utilizes Avidity Sequencing™ technology, ensuring over 90% of reads exceed Q30 quality, with minimal errors, low duplication rates, and reduced AT/GC bias. It supports easy data conversion to FASTQ files, offers compatibility with numerous assays, and provides cost-effective sequencing. This is our ideal companion for dedicated and fast-turnaround run set-up. For more detailed information, you can visit their website directly at https://www.elementbiosciences.com/products/aviti.
Whole Genome Sequencing
The whole genome sequence as the most comprehensive overview of its composition. Identify most of the variability accounted by SNPs, CNVs, PAVs, insertions, deletions, translocations along with its functional impact on the genetic code an organism. Dedicated technologies are applied for de novo reconstruction of personal genomes to an affordable price, providing an unbiased method to depict each individual human (and non-human) genome. See de novo - whole genome resequencing.
Low-pass sequencing
An alternative way to pursue genotyping/classification experiment is carried to a very low coverage per individual. This technique is adopted in several applications such as metagenomics, allele/SNP mining, Pop-Seq, Pool-Seq. Haplotype/organism identification will rely on a ‘horizontal’ coverage rather than a ‘vertical’ coverage. This analysis does not have sufficient information to detect structural variation, but dramatically reduces costs in large genotyping and metagenomics experiments. See metagenomics - bioinformatics
Nanopore Sequencing
Nanopore sequencing is empowering many applications by the ability to analyze DNA, RNA and their modifications with no limitation on sequence length. This is of particular importance when the goal is to resolve hard-to-sequence or repetitive regions that have so far hampered the possibility to decode structural and epigenetic variation. Also, direct RNA sequencing and full-length cDNA sequencing are providing unprecedented insight into the real strucure and abundance of transcripts isoforms.