---
title: "A duplex sequencing approach for high-sensitivity detection of genome-edited plants: a work in collaboration with the European Commission"
published: 2025-11-19 14:18:16.298916+00:00
locale: "it"
---

# A duplex sequencing approach for high-sensitivity detection of genome-edited plants: a work in collaboration with the European Commission

19 Nov 2025

We are happy to share that we have published a new paper in collaboration with the Joint Research Center of the European Commission! This work introduces a duplex NGS sequencing workflow that detects multiple genome‑editing events in plant DNA down to 0.1% variant frequency.

Crucially, the method shows that NGS can meet GMO traceability performance standards traditionally achieved with event‑specific PCR, while remaining assay-agnostic to the individual mutation—a key requirement when edits are numerous, small, or unknown a priori.

This work provides a proof of concept to fill the gap between regulatory traceability needs and the technical flexibility required to monitor modern genome editing.

[Read more](https://www.sciencedirect.com/science/article/pii/S2666566225000395?via%3Dihub)